Courtney+Dalton-BIO

Maple Syrup Urine Disease Hereditary disease due to deficiency of an enzyme involved in amino acid metabolism

**Description** Maple Syrup Urine Disease is a hereditary disease that makes urine have a smell of maple syrup, because three amino acids leucine,isoleucine,valine cannot be metabolized. Parts of proteins are not able to be broken down that causes chemicals in the blood stream.


 * Initial symptoms- **Avoiding food, feeding difficulties, comas, lethargy, seizures, urine that smells like maple syrup, also vomiting, are all symptoms of this diease. this diease can be detected at birth. This disease accurs also in peoples blood, sweat and urine.


 * Common Treatments:** to treat this disease u will need to keep a special diet, thats free of branched-chain amino acids. man made infant formula with low levels of amino-acids such as leucine,isoleucine and valine. Diet should be consent and permanent, for people who have this disease,Blood test will be frequent.
 * Prevention-** if an screening test shows you have MSUD or you're baby has MSUD, a follow up blood test for amino acids will be take right away. This disease is also hereditary so if you have it you cant get rid of it, you can treat it. But remember This disease is fatal.
 * Chromosome Information-** MSUD disease is assoicated with chromosome 19.
 * Populations:** There isnt a sertin place where this high popluated, but this disease accurs in citys or states where intermarriage is common. examples : Mennonite ( amish ), Pnnsylvania (U.S)