Kayla+N-bio

Canavan Disease __ Description __ Canavan disease is mainly inherited by children of eastern and central European Jewish descent and is a neurological disorder where the brain deteriorates. __ Symptoms __ The initial symptoms appear in infancy. Symptoms include: mental retardation, loss of acquired motor skills, abnormal muscle tones (stiffness or floppiness), and an abnormally large uncontrolled head. __ Treatments __ Many of the children diagnosed with this disease die before reaching ten years old. No treatments are available. __ Prevention or Control of the Disease __ Screening is now offered to the Ashkenazi Jewish population to attempt to control the disease. __ Chromosome associated with the disease __ Chromosome 17 and the ASPA gene on that chromosome is defective. __ How is the Disease Inherited __ The disease is inherited from when an individual inherits two recessive alleles. There is a 25% chance of having a child with the disease if both parents are carriers. __ Populations with Predispositions to the Disease __ Eastern European Jewish decent but it can affect others too. Works Cited [] [] [] []